Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation (ODE) models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.


Reference manual

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0.7.2-1 by Wenping Wang, 3 days ago

https://www.r-project.org, https://github.com/nlmixrdevelopment/RxODE

Report a bug at https://github.com/nlmixrdevelopment/RxODE/issues

Browse source code at https://github.com/cran/RxODE

Authors: Matthew L. Fidler [aut], Melissa Hallow [aut], Wenping Wang [aut, cre], Zufar Mulyukov [ctb], Justin Wilkins [ctb], Simon Frost [ctb], Heng Li [ctb], Yu Feng [ctb], Alan Hindmarsh [ctb], Linda Petzold [ctb], Ernst Hairer [ctb], Gerhard Wanner [ctb], J Colinge [ctb], Hadley Wickham [ctb], G Grothendieck [ctb], Robert Gentleman [ctb], Ross Ihaka [ctb], R core team [cph], odepack authors [cph]

Documentation:   PDF Manual  

Task views: Analysis of Pharmacokinetic Data

GPL (>= 2) license

Imports utils, methods, digest, rex, dparser, brew, memoise, magrittr, Rcpp, inline, Matrix, R.utils, PreciseSums, mvnfast, cli, crayon, n1qn1

Suggests knitr, nlme, shiny, tcltk, testthat, devtools, covr, rmarkdown, SnakeCharmR, rSymPy, dplyr, tidyr, tibble, curl, ggplot2, gridExtra, microbenchmark, scales, stringi, htmltools

Linking to dparser, Rcpp, RcppArmadillo, PreciseSums

Depended on by nlmixr.

See at CRAN