Facilities for Simulating from ODE-Based Models

Facilities for running simulations from ordinary differential equation (ODE) models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.


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install.packages("RxODE")

0.9.0-8 by Wenping Wang, 5 days ago


https://nlmixrdevelopment.github.io/RxODE/


Report a bug at https://github.com/nlmixrdevelopment/RxODE/issues


Browse source code at https://github.com/cran/RxODE


Authors: Matthew L. Fidler [aut] , Melissa Hallow [aut] , Wenping Wang [aut, cre] , Zufar Mulyukov [ctb] , Justin Wilkins [ctb] , Simon Frost [ctb] , Heng Li [ctb] , Yu Feng [ctb] , Alan Hindmarsh [ctb] , Linda Petzold [ctb] , Ernst Hairer [ctb] , Gerhard Wanner [ctb] , J Colinge [ctb] , Hadley Wickham [ctb] , G Grothendieck [ctb] , Robert Gentleman [ctb] , Ross Ihaka [ctb] , R core team [cph] , odepack authors [cph]


Documentation:   PDF Manual  


Task views: High-Performance and Parallel Computing with R, Analysis of Pharmacokinetic Data, Differential Equations


GPL (>= 2) license


Imports Matrix, PreciseSums, Rcpp, brew, cli, crayon, digest, dparser, ggforce, ggplot2, inline, magrittr, memoise, methods, mvnfast, n1qn1, pillar, rex, sys, units, utils, assertthat, lotri, remotes

Suggests knitr, DT, nlme, shiny, tcltk, testthat, usethis, devtools, covr, rmarkdown, SnakeCharmR, dplyr, tidyr, tibble, curl, gridExtra, microbenchmark, scales, stringi, htmltools, reticulate, rlang, installr

Linking to dparser, Rcpp, RcppArmadillo, PreciseSums


Imported by nlmixr.


See at CRAN