Analysis of Sex Differences in Omics Data for Complex Diseases

Tools to analyze sex differences in omics data for complex diseases. It includes functions for differential expression analysis using the 'limma' method , interaction testing between sex and disease, pathway enrichment with 'clusterProfiler' , and gene regulatory network (GRN) construction and analysis using 'igraph'. The package enables a reproducible workflow from raw data processing to biological interpretation.


Reference manual

It appears you don't have a PDF plugin for this browser. You can click here to download the reference manual.

install.packages("XYomics")

0.1.5 by Enrico Glaab, 2 months ago


Browse source code at https://github.com/cran/XYomics


Authors: Enrico Glaab [aut, cre] , Sophie Le Bars [aut] , Mohamed Soudy [aut] , Murodzhon Akhmedov [cph]


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports limma, igraph, edgeR, SeuratObject, Seurat, data.table, ggplot2, tidyr, grid, ggraph, dplyr, AnnotationDbi, ggrepel, Rcpp, cowplot, patchwork, methods, DESeq2, S4Vectors, clusterProfiler

Suggests R.utils, DT, gridExtra, knitr, htmltools, kableExtra, rmarkdown, stringr, ReactomePA, org.Hs.eg.db, MAST

Linking to Rcpp, BH


See at CRAN