Simulation-Based Design and Analysis of Dose-Finding Trials

An efficient implementation of the MCPMod (Multiple Comparisons and Modeling) method to support a simulation-based design and analysis of dose-finding trials with normally distributed, binary and count endpoints (Bretz et al. (2005) ).


Reference manual

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0.4 by Alex Dmitrienko, a year ago

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Authors: Alex Dmitrienko [aut, cre] , Alun Bedding [ctb] , John Cook [ctb]

Documentation:   PDF Manual  

GPL-3 license

Imports shiny, shinydashboard, devEMF, officer, flextable, Rcpp, RcppNumerical

Depends on mvtnorm

Suggests testthat, devtools, DoseFinding

Linking to Rcpp, RcppEigen, RcppNumerical

See at CRAN