MSigDB Gene Sets for Multiple Organisms in a Tidy Data Format

Provides the 'Molecular Signatures Database' (MSigDB) gene sets typically used with the 'Gene Set Enrichment Analysis' (GSEA) software (Subramanian et al. 2005 , Liberzon et al. 2015 , Castanza et al. 2023 ) as an R data frame. The package includes the human genes as listed in MSigDB as well as the corresponding symbols and IDs for frequently studied model organisms such as mouse, rat, pig, fly, and yeast.

msigdbr: MSigDB data frame

The msigdbr R package provides Molecular Signatures Database (MSigDB) gene sets:

in an R-friendly tidy format with one gene-to-gene-set mapping per row
for multiple frequently studied model organisms in addition to the original human genes
as gene symbols as well as NCBI Entrez and Ensembl IDs
without accessing external resources requiring an active internet connection

Check the documentation website for more information.