Amino Acid Substitution Effect Analyser

Given a protein multiple sequence alignment, it is daunting task to assess the effects of substitutions along sequence length. 'aaSEA' package is intended to help researchers to rapidly analyse property changes caused by single, multiple and correlated amino acid substitutions in proteins. Methods for identification of co-evolving positions from multiple sequence alignment are as described in : Pelé et al., (2017) .


Reference manual

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1.1.0 by Raja Sekhara Reddy D.M, 7 months ago

Browse source code at

Authors: Raja Sekhara Reddy D.M

Documentation:   PDF Manual  

GPL-3 license

Imports DT, networkD3, shiny, shinydashboard, magrittr, Bios2cor, seqinr, plotly, Hmisc

Suggests knitr, rmarkdown

See at CRAN