Phase I Dose Escalation Study Design for Vaccines

A Bayesian Phase I cancer vaccine trial design is implemented in this package. The design allows simultaneous evaluation of safety and immunogenicity outcomes in the context of vaccine studies. See Wang (2019) for the details of the Phase I cancer vaccine trial design.


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install.packages("visit")

2.1 by Chenguang Wang, 3 months ago


Browse source code at https://github.com/cran/visit


Authors: Zilu Wang [aut, cre] Chenguang Wang [aut, cre] Gary L Rosner [aut] Richard BS Roden [aut] Trustees of Columbia University [cph] (tools/make_cpp.R , R/stanmodels.R)


Documentation:   PDF Manual  


GPL (>= 3) license


Imports sqldf, parallel

Depends on methods, rstan, Rcpp

Suggests knitr, shiny, rmarkdown, pander, xtable

Linking to BH, Rcpp, rstan, RcppEigen, StanHeaders

System requirements: GNU make


See at CRAN