Inference and Prediction of ToxicoKinetic (TK) Models

The MOSAICbioacc application is a turn-key package providing bioaccumulation factors (BCF/BMF/BSAF) from a toxicokinetic (TK) model fitted to accumulation-depuration data. It is designed to fulfil the requirements of regulators when examining applications for market authorization of active substances. See Ratier et al. (2021) .


Reference manual

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1.0.2 by Aurélie Siberchicot, a month ago

Browse source code at

Authors: Virgile Baudrot [aut] , Sandrine Charles [aut] , Ohélia Gestin [ctb] , Mélina Kaag [aut] , Christelle Lopez [ctb] , Gauthier Multari [ctb] , Alain Pavé [ctb] , Aude Ratier [aut] , Aurélie Siberchicot [aut, cre]

Documentation:   PDF Manual  

MIT + file LICENSE license

Imports ggplot2, methods, Rcpp, RcppParallel, rstan, rstantools, testthat, ggmcmc, GGally, loo, stringr, stats, zoo

Suggests knitr, rmarkdown

Linking to BH, Rcpp, RcppEigen, RcppParallel, rstan, StanHeaders

System requirements: GNU make

See at CRAN