Linking Singe-Cell Transcriptomes Atween Contemporary Subpopulation Genomes

Given an RNA-seq derived cell-by-gene matrix and an DNA-seq derived copy number segmentation, LIAYSON predicts the number of clones present in a tumor, their size, the copy number profile of each clone and the clone membership of each single cell (Andor, N. & Lau, B., et al. (2018) ).


News

	CHANGES IN LIAYSON VERSION 1.0.2

OTHER CHANGES o Changed seed in clusterCells example to ensure compatibility with new implementation of function 'sample' in R 3.6

	CHANGES IN LIAYSON VERSION 1.0.1

NEW FEATURES o Separate preprocessing (aggregateSegmentExpression), main functionality (segmentExpression2CopyNumber), and postprocessing (clusterCells) steps are available

OTHER CHANGES o Completed documentation

Reference manual

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