Assessing the Integrity and Trustworthiness of Clinical Trials
Data
The integrity package implements the IPD Integrity Tool, a
structured and transparent framework for evaluating the integrity of
individual participant data (IPD) from randomised trials (see Hunter et
al. (2024) and ). It
supports users to identify potential issues, such as unusual data
patterns, implausible values, lack of expected correlations, date
violations, and inconsistencies. The package provides reproducible
workflows for screening, documenting and summarising integrity concerns,
and may be applied by evidence synthesists, editors, and others to
determine whether a randomised trial may be considered sufficiently
trustworthy to contribute to the evidence base that informs policy and
practice.