Simulation of Cohort Platform Trials for Combination Treatments

A collection of functions dedicated to simulating staggered entry platform trials whereby the treatment under investigation is a combination of two active compounds. In order to obtain approval for this combination therapy, superiority of the combination over the two active compounds and superiority of the two active compounds over placebo need to be demonstrated. A more detailed description of the design can be found in Meyer et al. (2021).


Reference manual

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1.0.0 by Elias Laurin Meyer, a month ago

Browse source code at

Authors: Elias Laurin Meyer [aut, cre]

Documentation:   PDF Manual  

GPL-3 license

Imports dplyr, purrr, ggplot2, plotly, tidyr, parallel, doParallel, foreach, openxlsx, forcats, epitools, zoo

Suggests knitr, rmarkdown, DT, gtools

See at CRAN