Genome-Wide Association Study with SLOPE

Genome-wide association study (GWAS) performed with SLOPE, short for Sorted L-One Penalized Estimation, a method for estimating the vector of coefficients in linear model. In the first step of GWAS, SNPs are clumped according to their correlations and distances. Then, SLOPE is performed on data where each clump has one representative.


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Reference manual

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install.packages("geneSLOPE")

0.37.0 by Piotr Sobczyk, 10 months ago


https://github.com/psobczyk/geneSLOPE


Report a bug at https://github.com/psobczyk/geneSLOPE/issues


Browse source code at https://github.com/cran/geneSLOPE


Authors: Damian Brzyski [aut], Christine Peterson [aut], Emmanuel J. Candes [aut], Malgorzata Bogdan [aut], Chiara Sabatti [aut], Piotr Sobczyk [cre, aut]


Documentation:   PDF Manual  


GPL-3 license


Imports ggplot2, bigmemory, grid, utils, stats

Depends on SLOPE

Suggests shiny, knitr, rmarkdown, testthat


See at CRAN