Differential Network Analysis using Gene Pathways

Integrates pathway information into the differential network analysis of two gene expression datasets as described in Grimes, Potter, and Datta (2019) . Provides summary functions to break down the results at the pathway, gene, or individual connection level. The differential networks for each pathway of interest can be plotted, and the visualization will highlight any differentially expressed genes and all of the gene-gene associations that are significantly differentially connected.


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install.packages("dnapath")

0.6.3 by Tyler Grimes, 9 days ago


Browse source code at https://github.com/cran/dnapath


Authors: Tyler Grimes and Somnath Datta


Documentation:   PDF Manual  


GPL-2 | GPL-3 license


Imports Rcpp, Rdpack, dplyr, tibble, stats, methods, curl, graphics, grDevices, utils

Suggests testthat, knitr, rmarkdown, readr, bc3net, corpcor, DWLasso, GENIE3, huge, igraph, minet, ggplot2, SeqNet, biomaRt, reactome.db

Linking to Rcpp, RcppArmadillo


See at CRAN