Perform HTS-SIP analyses such as high resolution stable isotope probing (HR-SIP),
multi-window high resolution stable isotope probing (MW-HR-SIP), and quantitative stable
isotope probing (q-SIP). More information on HR-SIP, MW-HR-SIP, and q-SIP can be
1) Pepe-Ranney, Charles, Ashley N. Campbell, Chantal N. Koechli, Sean Berthrong, and
Daniel H. Buckley. 2016. "Unearthing the Ecology of Soil Microorganisms Using a
High Resolution DNA-SIP Approach to Explore Cellulose and Xylose Metabolism in
Soil." Terrestrial Microbiology, 703.
HTSSIP is an R package for analyzing high throughput sequence data from nucleotide stable isotope probing (DNA- & RNA-SIP) experiments.
Identifying community-level isotope incorporatation
Identifying isotope incorporators
A good place to start is the HTSSIP introduction vignette.
References in the HTSSIP introduction vignette.
To get the current released version from CRAN:
install.packages("HTSSIP") # sorry: the package is not yet on CRAN
To get the current development version from github: