Execute Pharmacometric Models Using 'shiny'

Execute Nonlinear Mixed Effects (NLME) models for pharmacometrics using a 'shiny' interface. Specify engine parameters and select from different run options, including simple estimation, stepwise covariate search, bootstrapping, simulation, visual predictive check, and more. Models are executed using the 'Certara.RsNLME' package.

RsNLME Model Executor

Overview

Certara.RsNLME.ModelExecutor is an R package and Shiny application used to execute an RsNLME model.

Use the GUI to add additional output tables, specify engine parameters, select various run types, and more!

Installation

Windows

install.packages("Certara.RsNLME.ModelExecutor",
                 repos = c("https://certara.jfrog.io/artifactory/certara-cran-release-public/",
                           "https://cloud.r-project.org"),
                 method = "libcurl")

Linux

install.packages("Certara.RsNLME.ModelExecutor",
                 repos = c("https://certara.jfrog.io/artifactory/certara-cran-release-public/",
                           "https://cloud.r-project.org"))

Usage

Use Certara.RsNLME.ModelExecutor to launch the model execution interface with a model object.

library(Certara.RsNLME.ModelExecutor)
library(Certara.RsNLME)

model <- pkmodel(numCompartments=2,
                 data = pkData,
                 ID = "Subject",
                 Time = "Act_Time",
                 A1 = "Amount",
                 CObs = "Conc")

modelExecutorUI(model = model)