Signature Survival Analysis

When multiple Cox proportional hazard models are performed on clinical data (month or year and status) and a set of differential expressions of genes, the results (Hazard risks, z-scores and p-values) can be used to create gene-expression signatures. Weights are calculated using the survival p-values of genes and are utilized to calculate expression values of the signature across the selected genes in all patients in a cohort. A Single or multiple univariate or multivariate Cox proportional hazard survival analyses of the patients in one cohort can be performed by using the gene-expression signature and visualized using our survival plots.


Reference manual

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install.packages("signatureSurvival")

1.0.0 by Yuan-De Tan, 3 years ago


Browse source code at https://github.com/cran/signatureSurvival


Authors: Yuan-De Tan [aut, cre] , Yuguang Ban [ctb]


Documentation:   PDF Manual  


GPL (>= 3) license


Imports stats, utils, graphics, grDevices, dplyr, forestplot, gplots, gtools, survival, survminer, ggplot2

Suggests Rmisc


See at CRAN