Pharmacometric and Pharmacokinetic Toolkit

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) < http://lixoft.com/wp-content/uploads/2016/03/PKPDlibrary.pdf>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).


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Reference manual

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install.packages("pmxTools")

0.1.3 by Justin Wilkins, a month ago


https://github.com/kestrel99/pmxTools


Report a bug at https://github.com/kestrel99/pmxTools/issues


Browse source code at https://github.com/cran/pmxTools


Authors: Justin Wilkins [aut, cre] , Bill Denney [aut] , Rik Schoemaker [aut] , Leonid Gibiansky [ctb] , Andrew Hooker [ctb] , E. Niclas Jonsson [ctb] , Mats O. Karlsson [ctb] , John Johnson [ctb]


Documentation:   PDF Manual  


Task views: Analysis of Pharmacokinetic Data


GPL-2 license


Imports ggplot2, ggrepel, gridExtra

Depends on MASS, stringr, XML

Suggests testthat


See at CRAN