Genome-Wide Structural Equation Modeling

Melds genome-wide association tests with structural equation modeling (SEM) using 'OpenMx'. This package contains low-level C/C++ code to rapidly read genetic data encoded in U.K. Biobank or 'plink' formats. Prebuilt modeling options include one and two factor models. Alternately, analyses may utilize arbitrary, user-provided SEMs. See Verhulst, Maes, & Neale (2017) for details. An updated manuscript is in preparation.


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install.packages("gwsem")

0.1.5 by Joshua N. Pritikin, 4 days ago


https://github.com/jpritikin/gwsem


Report a bug at https://github.com/jpritikin/gwsem/issues


Browse source code at https://github.com/cran/gwsem


Authors: Joshua N. Pritikin [aut, cre] , Bradley Verhulst [cph] , Gavin Band [cph] , Yann Collet [cph] , Facebook , Inc. [cph] , Yuta Mori [cph] , Shaun Purcell [cph] , Christopher Chang [cph] , Wojciech Mula [cph] , Kim Walisch [cph]


Documentation:   PDF Manual  


GPL (>= 3) license


Imports data.table, methods

Depends on OpenMx

Suggests testthat, MASS, covr, knitr, rmarkdown, qqman

Linking to BH

System requirements: GNU make


See at CRAN