Generalised Survival Trial Assessment Tool Environment

Provides tools to assist planning and monitoring of time-to-event trials under complicated censoring assumptions and/or non-proportional hazards. There are three main components: The first is analytic calculation of predicted time-to-event trial properties, providing estimates of expected hazard ratio, event numbers and power under different analysis methods. The second is simulation, allowing stochastic estimation of these same properties. Thirdly, it provides parametric event prediction using blinded trial data, including creation of prediction intervals. Methods are based upon numerical integration and a flexible object-orientated structure for defining event, censoring and recruitment distributions (Curves).


Reference manual

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1.4.0 by James Bell, a year ago

Browse source code at

Authors: James Bell [aut, cre] , Jasmin Ruehl [ctb]

Documentation:   PDF Manual  

GPL-3 license

Imports foreach, doParallel, shiny, shinythemes, survival, methods

Suggests testthat, knitr, rmarkdown

See at CRAN