Clinical Trial Design and Data Analysis Functions

Utilities to make your clinical collaborations easier if not fun. It contains functions for designing studies such as Simon 2-stage and group sequential designs and for data analysis such as Jonckheere-Terpstra test and estimating survival quantiles.


Reference manual

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1.0.15 by Venkatraman E. Seshan, 4 years ago

Browse source code at

Authors: Venkatraman E. Seshan

Documentation:   PDF Manual  

Task views: Clinical Trial Design, Monitoring, and Analysis, Survival Analysis

GPL (>= 2) license

Imports mvtnorm

Depends on graphics, stats

Suggests survival

Imported by hctrial, ph2mult.

Depended on by CTP, EurosarcBayes, OptInterim, binseqtest, gMWT, gen2stage.

Suggested by ADCT, RcmdrPlugin.EZR, ph2bye.

See at CRAN