Adaptive Design in Clinical Trials

Existing adaptive design methods in clinical trials. The package includes power, stopping boundaries (sample size) calculation functions for two-group group sequential designs, adaptive design with coprimary endpoints, biomarker-informed adaptive design, etc.


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Reference manual

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install.packages("ADCT")

0.1.0 by Yalin Zhu, 2 years ago


Browse source code at https://github.com/cran/ADCT


Authors: Yalin Zhu


Documentation:   PDF Manual  


GPL (>= 2) license


Imports stats, mvtnorm

Suggests clinfun, gsDesign


See at CRAN