Simulation and Analysis Tools for Clinical Dose Response Modeling

Bayesian and ML Emax model fitting, graphics and simulation for clinical dose response. The summary data from the dose response meta-analyses in Thomas, Sweeney, and Somayaji (2014) and Thomas and Roy (2016) Wu, Banerjee, Jin, Menon, Martin, and Heatherington(2017) are included in the package. The prior distributions for the Bayesian analyses default to the posterior predictive distributions derived from these references.


Reference manual

It appears you don't have a PDF plugin for this browser. You can click here to download the reference manual.

install.packages("clinDR")

2.5.3 by Neal Thomas, 25 days ago


Browse source code at https://github.com/cran/clinDR


Authors: Neal Thomas [aut, cre] , Jing Wu [aut] , Mike K. Smith [aut] , Budhaditya Goswami [aut] , Satrajit Roychoudhury [aut]


Documentation:   PDF Manual  


GPL (>= 2) license


Imports foreach, graphics, DoseFinding, stats, mvtnorm, utils, parallel, doParallel, ggplot2, tidyr, purrr, tibble, dplyr, glue, waiter, officer

Depends on rstan, shiny

Suggests knitr, rmarkdown


Depended on by ememax.

Suggested by BayesianMCPMod.


See at CRAN