Biomarker Threshold Models

Contains tools to fit both predictive and prognostic biomarker effects using biomarker threshold models and continuous threshold models. Evaluate the treatment effect, biomarker effect and treatment-biomarker interaction using probability index measurement. Test for treatment-biomarker interaction using residual bootstrap method.


Reference manual

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1.16 by Bingshu E. Chen, a year ago

Browse source code at

Authors: Bingshu E. Chen

Documentation:   PDF Manual  

GPL (>= 2) license

Imports methods

Depends on coda, ggplot2, MASS, survival

See at CRAN