Patient Subgroup Identification for Clinical Drug Development

Implementation of Sequential BATTing (bootstrapping and aggregating of thresholds from trees) for developing threshold-based multivariate (prognostic/predictive) biomarker signatures. Variable selection is automatically built-in. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output. Detail algorithms are described in Huang et al (2017) .


Reference manual

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install.packages("SubgrpID")

0.14 by Xin Huang, 7 months ago


https://xhuang4.github.io/seqbatting-html/


Browse source code at https://github.com/cran/SubgrpID


Authors: Xin Huang [aut, cre, cph] , Yan Sun [aut] , Saptarshi Chatterjee [aut] , Paul Trow [aut]


Documentation:   PDF Manual  


GPL (>= 2) license


Imports glmnet, MASS, rpart, survival, Matrix, ggplot2


See at CRAN