SNP-Set (Sequence) Kernel Association Test

Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values.


Reference manual

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2.0.1 by Seunggeun (Shawn) Lee, a month ago

Browse source code at

Authors: Seunggeun (Shawn) Lee and Zhangchen Zhao , with contributions from Larisa Miropolsky and Michael Wu

Documentation:   PDF Manual  

GPL (>= 2) license

Depends on Matrix, SPAtest

Imported by GBJ, MetaSKAT, SMUT, zfa.

Depended on by FSTpackage, GenoScan, LGEWIS, LGRF, Mega2R, WGScan.

Suggested by BGData, FastKM, seqminer.

See at CRAN