Gene‐based Association Tests of Zero‐inflated Count Phenotype for Rare Variants

Gene‐based association tests to model count data with excessive zeros and rare variants using zero-inflated Poisson/zero-inflated negative Binomial regression framework. This method was originally described by Fan, Sun, and Li in Genetic Epidemiology 46(1):73-86 .

ZIM4rv

Overview

ZIM4rv is a package for precisely modeling zero‐inflated count phenotype for rare variants. This package primarily implements the genetic association test between zero‐inflated count phenotype and rare variants.

Installation

You can install the development version of ZIM4rv from Github with:

# install.packages("devtools")
devtools::install_github("fanx0037/ZIM4rv")

You can also get the official release version from CRAN

install.packages("ZIM4rv")

Usage

The following help page will provide quick references for ZIM4rv package and its main functions:

library(ZIM4rv)
?zimfrv