A Fast and Light Package to Compute Polygenic Risk Scores

Quickly computes polygenic scores from GWAS summary statistics of either case-control or quantitative traits, without LD matrix computation or parameter tuning. Reales,G., Vigorito, E., Kelemen,M., Wallace,C. (2021) "R√°pidoPGS: A rapid polygenic score calculator for summary GWAS data without a test dataset".


Reference manual

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2.1.0 by Guillermo Reales, 7 months ago

Browse source code at https://github.com/cran/RapidoPGS

Authors: Guillermo Reales [aut, cre] , Chris Wallace [aut] , Olly Burren [ctb]

Documentation:   PDF Manual  

GPL-3 license

Imports dplyr, GenomicRanges, IRanges, bigsnpr, coloc, bigreadr

Depends on data.table, RCurl, curl

Suggests knitr, rmarkdown

See at CRAN