Microbiome Based Sum of Powered Score (MiSPU) Tests

There is an increasing interest in investigating how the compositions of microbial communities are associated with human health and disease. In this package, we present a novel global testing method called aMiSPU, that is highly adaptive and thus high powered across various scenarios, alleviating the issue with the choice of a phylogenetic distance. Our simulations and real data analysis demonstrated that aMiSPU test was often more powerful than several competing methods while correctly controlling type I error rates.


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install.packages("MiSPU")

1.0 by Chong Wu, 3 years ago


Browse source code at https://github.com/cran/MiSPU


Authors: Chong Wu , Wei Pan


Documentation:   PDF Manual  


GPL-2 license


Imports Rcpp

Depends on vegan, ape, aSPU, cluster

Suggests ade4

Linking to Rcpp, RcppArmadillo


See at CRAN