Implements the Genomic Random Interval (GRIN) framework for
identifying genomic loci affected by genomic lesions more frequently than
expected by chance. Supports multiple lesion classes, lesion constellation
analysis, exon-level target-size modeling, genomic lesion visualization,
and gene-level association analyses linking genomic lesions or gene
expression with binary and time-to-event clinical outcomes. Includes tools
for retrieving versioned GRCh38 Ensembl gene, exon, and regulatory-element
annotations. The statistical framework is described in Pounds et al. (2013)