Analysis of Copy Number Signatures

A workflow to generate and analyze signatures based on copy number data using non-negative matrix factorization (NMF) in an approach similar to that used in mutational signatures. It can be used to extract features from Copy number segment data and use that to find a subset of copy number signatures which can be further used to correlate with other relevant data. For more on 'NMF' see Gaujoux (2013) .


Reference manual

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install.packages("CNSigs")

0.1.1 by Shawn Striker, 3 months ago


Browse source code at https://github.com/cran/CNSigs


Authors: David Tallman [aut] , Shawn Striker [cre, ctb] , Daniel Stover [cph]


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports methods, doParallel, foreach, flexmix, lsei, ggplot2, snow, cowplot, pheatmap, RColorBrewer, viridisLite, colorspace, stats, utils

Depends on NMF

Suggests knitr, rmarkdown


See at CRAN