Automated and Early Detection of Disease Outbreaks

A powerful tool for automating the early detection of disease outbreaks in time series data. 'aeddo' employs advanced statistical methods, including hierarchical models, in an innovative manner to effectively characterize outbreak signals. It is particularly useful for epidemiologists, public health professionals, and researchers seeking to identify and respond to disease outbreaks in a timely fashion. For a detailed reference on hierarchical models, consult Henrik Madsen and Poul Thyregod's book (2011), ISBN: 9781420091557.

Fitting (Exponential/Diffusion) RT-MPT Models

Fit (exponential or diffusion) response-time extended multinomial processing tree (RT-MPT) models by Klauer and Kellen (2018) and Klauer, Hartmann, and Meyer-Grant (submitted). The RT-MPT class not only incorporate frequencies like traditional multinomial processing tree (MPT) models, but also latencies. This enables it to estimate process completion times and encoding plus motor execution times next to the process probabilities of traditional MPTs. 'rtmpt' is a hierarchical Bayesian framework and posterior samples are sampled using a Metropolis-within-Gibbs sampler (for exponential RT-MPTs) or Hamiltonian-within-Gibbs sampler (for diffusion RT-MPTs).

Dynamic Models for Confidence and Response Time Distributions

Provides density functions for the joint distribution of choice, response time and confidence for discrete confidence judgments as well as functions for parameter fitting, prediction and simulation for various dynamical models of decision confidence. All models are explained in detail by Hellmann et al. (2023; Preprint available at < https://osf.io/9jfqr/>, published version: ). Implemented models are the dynaViTE model, dynWEV model, the 2DSD model (Pleskac & Busemeyer, 2010, ), and various race models. C++ code for dynWEV and 2DSD is based on the 'rtdists' package by Henrik Singmann.

Estimated Marginal Means, aka Least-Squares Means

Obtain estimated marginal means (EMMs) for many linear, generalized linear, and mixed models. Compute contrasts or linear functions of EMMs, trends, and comparisons of slopes. Plots and other displays. Least-squares means are discussed, and the term "estimated marginal means" is suggested, in Searle, Speed, and Milliken (1980) Population marginal means in the linear model: An alternative to least squares means, The American Statistician 34(4), 216-221 .

Complete Functional Regulation Analysis

Calculates complete functional regulation analysis and visualize the results in a single heatmap. The provided example data is for biological data but the methodology can be used for large data sets to compare quantitative entities that can be grouped. For example, a store might divide entities into cloth, food, car products etc and want to see how sales changes in the groups after some event. The theoretical background for the calculations are provided in New insights into functional regulation in MS-based drug profiling, Ana Sofia Carvalho, Henrik Molina & Rune Matthiesen, Scientific Reports .

Item Selection and Exhaustive Search for Rasch Models

Automation of the item selection processes for Rasch scales by means of exhaustive search for suitable Rasch models (dichotomous, partial credit, rating-scale) in a list of item-combinations. The item-combinations to test can be either all possible combinations or item-combinations can be defined by several rules (forced inclusion of specific items, exclusion of combinations, minimum/maximum items of a subset of items). Tests for model fit and item fit include ordering of the thresholds, item fit-indices, likelihood ratio test, Martin-Löf test, Wald-like test, person-item distribution, person separation index, principal components of Rasch residuals, empirical representation of all raw scores or Rasch trees for detecting differential item functioning. The tests, their ordering and their parameters can be defined by the user. For parameter estimation and model tests, functions of the packages 'eRm', 'psychotools' or 'pairwise' can be used.

Dependency-Aware Scenario Exploration for Group Sequential Designs

Provides systematic, dependency-aware exploration of group sequential designs created with 'gsDesign'. Supports reproducible grid and random search over user-defined candidate sets, parallel evaluation via the 'future' framework, standardized metric extraction, and auditable reporting for design-space evaluation and trade-off analysis. Methods for group sequential design are described in Anderson (2025) . The 'future' framework for parallel processing is described in Bengtsson (2021) .

Bridge Sampling for Marginal Likelihoods and Bayes Factors

Provides functions for estimating marginal likelihoods, Bayes factors, posterior model probabilities, and normalizing constants in general, via different versions of bridge sampling (Meng & Wong, 1996, < https://www3.stat.sinica.edu.tw/statistica/j6n4/j6n43/j6n43.htm>). Gronau, Singmann, & Wagenmakers (2020) .

A Crew Launcher Plugin for AWS Batch

In computationally demanding analysis projects, statisticians and data scientists asynchronously deploy long-running tasks to distributed systems, ranging from traditional clusters to cloud services. The 'crew.aws.batch' package extends the 'mirai'-powered 'crew' package with a worker launcher plugin for AWS Batch. Inspiration also comes from packages 'mirai' by Gao (2023) < https://github.com/r-lib/mirai>, 'future' by Bengtsson (2021) , 'rrq' by FitzJohn and Ashton (2023) < https://github.com/mrc-ide/rrq>, 'clustermq' by Schubert (2019) ), and 'batchtools' by Lang, Bischl, and Surmann (2017). .

Crew Launcher Plugins for Traditional High-Performance Computing Clusters

In computationally demanding analysis projects, statisticians and data scientists asynchronously deploy long-running tasks to distributed systems, ranging from traditional clusters to cloud services. The 'crew.cluster' package extends the 'mirai'-powered 'crew' package with worker launcher plugins for traditional high-performance computing systems. Inspiration also comes from packages 'mirai' by Gao (2023) < https://github.com/r-lib/mirai>, 'future' by Bengtsson (2021) , 'rrq' by FitzJohn and Ashton (2023) < https://github.com/mrc-ide/rrq>, 'clustermq' by Schubert (2019) ), and 'batchtools' by Lang, Bischl, and Surmann (2017). .