Power Analysis for Generalised Linear Mixed Models by Simulation

Calculate power for generalised linear mixed models, using simulation. Designed to work with models fit using the 'lme4' package. Described in Green and MacLeod, 2016 .

Linear Mixed Models - An Introduction with Applications in Veterinary Research

R Codes and Datasets for Duchateau, L. and Janssen, P. and Rowlands, G. J. (1998). Linear Mixed Models. An Introduction with applications in Veterinary Research. International Livestock Research Institute.

Scale Mixture of Skew-Normal Linear Mixed Models

It fits scale mixture of skew-normal linear mixed models using an expectation–maximization (EM) type algorithm, including some possibilities for modeling the within-subject dependence. Details can be found in Schumacher, Lachos and Matos (2021) .

Post-Estimation Functions for Generalized Linear Mixed Models

Several functions for working with mixed effects regression models for limited dependent variables. The functions facilitate post-estimation of model predictions or margins, and comparisons between model predictions for assessing or probing moderation. Additional helper functions facilitate model comparisons and implements simulation-based inference for model predictions of alternative-specific outcome models. See also, Melamed and Doan (2024, ISBN: 978-1032509518).

Fast Fitting of Stable Isotope Mixing Models with Covariates

Fast fitting of Stable Isotope Mixing Models in R. Allows for the inclusion of covariates. Also has built-in summary functions and plot functions which allow for the creation of isospace plots. Variational Bayes is used to fit these models, methods as described in: Tran et al., (2021) .

Maximum Likelihood Estimation for Generalized Linear Mixed Models

Maximum likelihood estimation for generalized linear mixed models via Monte Carlo EM. For a description of the algorithm see Brian S. Caffo, Wolfgang Jank and Galin L. Jones (2005) .

Mixed Model Association Test for GEne-Environment Interaction

Use a 'glmmkin' class object (GMMAT package) from the null model to perform generalized linear mixed model-based single-variant and variant set main effect tests, gene-environment interaction tests, and joint tests for association, as proposed in Wang et al. (2020) .

Estimate (Generalized) Linear Mixed Models with Factor Structures

Utilizes the 'lme4' and 'optimx' packages (previously the optim() function from 'stats') to estimate (generalized) linear mixed models (GLMM) with factor structures using a profile likelihood approach, as outlined in Jeon and Rabe-Hesketh (2012) and Rockwood and Jeon (2019) . Factor analysis and item response models can be extended to allow for an arbitrary number of nested and crossed random effects, making it useful for multilevel and cross-classified models.

Generalized Fiducial Inference for Normal Linear Mixed Models

Simulation of the generalized fiducial distribution for normal linear mixed models with interval data. Fiducial inference is somehow similar to Bayesian inference, in the sense that it is based on a distribution that represents the uncertainty about the parameters, like the posterior distribution in Bayesian statistics. It does not require a prior distribution, and it yields results close to frequentist results. Reference: Cisewski and Hannig (2012) .

Variable Selection in Linear Mixed Models for SNP Data

Fit penalized multivariable linear mixed models with a single random effect to control for population structure in genetic association studies. The goal is to simultaneously fit many genetic variants at the same time, in order to select markers that are independently associated with the response. Can also handle prior annotation information, for example, rare variants, in the form of variable weights. For more information, see the website below and the accompanying paper: Bhatnagar et al., "Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models", 2020, .