Deficit Index (DI)

A set of utilities for calculating the Deficit (frailty) Index (DI) in gerontological studies. The deficit index was first proposed by Arnold Mitnitski and Kenneth Rockwood and represents a proxy measure of aging and also can be served as a sensitive predictor of survival. For more information, see (i)"Accumulation of Deficits as a Proxy Measure of Aging" by Arnold B. Mitnitski et al. (2001), The Scientific World Journal 1, ; (ii) "Frailty, fitness and late-life mortality in relation to chronological and biological age" by Arnold B Mitnitski et al. (2001), BMC Geriatrics2002 2(1), .

Regional Vulnerability Index

The Regional Vulnerability Index (RVI), a statistical measure of brain structural abnormality, quantifies an individual's similarity to the expected pattern (effect size) of deficits in schizophrenia (Kochunov P, Fan F, Ryan MC, et al. (2020) ).

Tools for Pre-Processing Emission-Excitation-Matrix (EEM) Fluorescence Data

Provides various tools for preprocessing Emission-Excitation-Matrix (EEM) for Parallel Factor Analysis (PARAFAC). Different methods are also provided to calculate common metrics such as humification index and fluorescence index.

Calculates and Analyzes the Proliferative Index

Provides functions for calculating and analyzing the proliferative index (PI) from an RNA-seq dataset. As described in Ramaker & Lasseigne, et al. bioRxiv, 2016 .

Simple Blinding Index for Randomized Controlled Trials

Computes a simple blinding index for randomized controlled trials introduced in Petroff, Bacak, Dagres, Dilk, Wachter: A simple blinding index for randomized controlled trials. Contemp Clin Trials Commun. 2024 Nov 26;42:101393. . PMID: 39686958.

Predictive Information Index ('PII')

A simple implementation of the Predictive Information Index ('PII') using mutual information and entropy from the 'infotheo' package. For related methodology, see Wells (2025) < https://github.com/TheotherDrWells/piiR>.

Calculate the Dutch Air Quality Index (LKI)

Calculates the dutch air quality index (LKI). This index was created on the basis of scientific studies of the health effects of air pollution. From these studies it can be deduced at what concentrations a certain percentage of the population can be affected. For more information see: < https://www.rivm.nl/bibliotheek/rapporten/2014-0050.pdf>.

Within Outlying Mean Indexes: Refining the OMI Analysis

Complementary indexes calculation to the Outlying Mean Index analysis to explore niche shift of a community and biological constraint within an Euclidean space, with graphical displays. For details see Karasiewicz et al. (2017) .

Forward Selection using Concordance/C-Index

Performs forward model selection, using the C-index/concordance in survival analysis models.

Index of Multiple Deprivation Data for the UK

Index of Multiple Deprivation for UK nations at various geographical levels. In England, deprivation data is for Lower Layer Super Output Areas, Middle Layer Super Output Areas, Wards, and Local Authorities based on data from < https://www.gov.uk/government/statistics/english-indices-of-deprivation-2019>. In Wales, deprivation data is for Lower Layer Super Output Areas, Middle Layer Super Output Areas, Wards, and Local Authorities based on data from < https://gov.wales/welsh-index-multiple-deprivation-full-index-update-ranks-2019>. In Scotland, deprivation data is for Data Zones, Intermediate Zones, and Council Areas based on data from < https://simd.scot>. In Northern Ireland, deprivation data is for Super Output Areas and Local Government Districts based on data from < https://www.nisra.gov.uk/statistics/deprivation/northern-ireland-multiple-deprivation-measure-2017-nimdm2017>. The 'IMD' package also provides the composite UK index developed by < https://github.com/mysociety/composite_uk_imd>.