Knowledge Discovery by Accuracy Maximization

A self-guided, weakly supervised learning algorithm for feature extraction from noisy and high-dimensional data. It facilitates the identification of patterns that reflect underlying group structures across all samples in a dataset. The method incorporates a novel strategy to integrate spatial information, improving the clarity of results in spatially resolved data.

Implement Fleming-Viot-Dependent Dirichlet Processes

A Bayesian Nonparametric model for the study of time-evolving frequencies, which has become renowned in the study of population genetics. The model consists of a Hidden Markov Model (HMM) in which the latent signal is a distribution-valued stochastic process that takes the form of a finite mixture of Dirichlet Processes, indexed by vectors that count how many times each value is observed in the population. The package implements methodologies presented in Ascolani, Lijoi and Ruggiero (2021) and Ascolani, Lijoi and Ruggiero (2023) that make it possible to study the process at the time of data collection or to predict its evolution in future or in the past.

Spatial KWD for Large Spatial Maps

Contains efficient implementations of Discrete Optimal Transport algorithms for the computation of Kantorovich-Wasserstein distances between pairs of large spatial maps (Bassetti, Gualandi, Veneroni (2020), ). All the algorithms are based on an ad-hoc implementation of the Network Simplex algorithm. The package has four main helper functions: compareOneToOne() (to compare two spatial maps), compareOneToMany() (to compare a reference map with a list of other maps), compareAll() (to compute a matrix of distances between a list of maps), and focusArea() (to compute the KWD distance within a focus area). In non-convex maps, the helper functions first build the convex-hull of the input bins and pad the weights with zeros.

A Service for Tidy Transcriptomics Software Suite

It provides generic methods that are used by more than one package, avoiding conflicts. This package will be imported by 'tidySingleCellExperiment' and 'tidyseurat'.

Articulatory Data Processing in R

A tool for processing Articulate Assistant Advanced™ (AAA) ultrasound tongue imaging data and Carstens AG500/1 electro-magnetic articulographic data.

Tidy Prediction and Plotting of Generalised Additive Models

Provides functions that compute predictions from Generalised Additive Models (GAMs) fitted with 'mgcv' and return them as a tibble. These can be plotted with a generic plot()-method that uses 'ggplot2' or plotted as any other data frame. The main function is predict_gam().

Brings Seurat to the Tidyverse

It creates an invisible layer that allow to see the 'Seurat' object as tibble and interact seamlessly with the tidyverse.

A Tidy Implementation of Heatmap

This is a tidy implementation for heatmap. At the moment it is based on the (great) package 'ComplexHeatmap'. The goal of this package is to interface a tidy data frame with this powerful tool. Some of the advantages are: Row and/or columns colour annotations are easy to integrate just specifying one parameter (column names). Custom grouping of rows is easy to specify providing a grouped tbl. For example: df %>% group_by(...). Labels size adjusted by row and column total number. Default use of Brewer and Viridis palettes.

Select Variables for Optimal Clustering

Finding hidden clusters in structured data can be hindered by the presence of masking variables. If not detected, masking variables are used to calculate the overall similarities between units, and therefore the cluster attribution is more imprecise. The algorithm q-vars implements an optimization method to find the variables that most separate units between clusters. In this way, masking variables can be discarded from the data frame and the clustering is more accurate. Tests can be found in Benati et al.(2017) .

Conversion of Nuclear Magnetic Resonance Spectra in Audio Files

A collection of functions for converting and visualization the free induction decay of mono dimensional nuclear magnetic resonance (NMR) spectra into an audio file. It facilitates the conversion of Bruker datasets in files WAV. The sound of NMR signals could provide an alternative to the current representation of the individual metabolic fingerprint and supply equally significant information. The package includes also NMR spectra of the urine samples provided by four healthy donors. Based on Cacciatore S, Saccenti E, Piccioli M. Hypothesis: the sound of the individual metabolic phenotype? Acoustic detection of NMR experiments. OMICS. 2015;19(3):147-56. .