Bootstrap Imputation for Single-Cell RNA-Seq Data

Given a log-transformed expression matrix and list of informative genes: subsample informative genes, cluster samples using shared nearest neighbors clustering, estimate missing expression values with the distribution mean of means extrapolated from these cell clusterings, and return an imputed expression matrix. See Tracy, S., Yuan, G.C. and Dries, R. (2019) for more details.


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install.packages("rescue")

1.0.3 by Sam Tracy, 3 months ago


https://github.com/seasamgo/rescue


Report a bug at http://github.com/seasamgo/rescue/issues


Browse source code at https://github.com/cran/rescue


Authors: Sam Tracy & Ruben Dries


Documentation:   PDF Manual  


GPL-2 | GPL-3 license


Imports data.table, dbscan, igraph, irlba, Matrix, methods, parallel, reticulate

Depends on utils

Suggests knitr, rmarkdown


See at CRAN