Simultaneous Enrichment Analysis

SEA performs simultaneous feature-set testing for (gen)omics data. It tests the unified null hypothesis controls the family-wise error rate for all possible pathways. The unified null hypothesis is defined as: "The proportion of true features in the set is less than or equal to the threshold c", where c is selected by the user. Family-wise error rate control is provided through use of closed testing with Simes test. For more information on closed testing with Simes see Goeman et al. (2019) and for more information about the properties and performance of SEA procedure see Ebrahimpoor et al. (2019) .


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install.packages("rSEA")

2.1.1 by Mitra Ebrahimpoor, 15 days ago


https://github.com/mitra-ep/rSEA


Browse source code at https://github.com/cran/rSEA


Authors: Mitra Ebrahimpoor


Documentation:   PDF Manual  


GPL (>= 2) license


Depends on hommel, ggplot2

Suggests knitr, rmarkdown


See at CRAN