Simultaneous Enrichment Analysis

SEA performs simultaneous feature-set testing for (gen)omics data. It tests the unified null hypothesis and controls the family-wise error rate for all possible pathways. The unified null hypothesis is defined as: "The proportion of true features in the set is less than or equal to a threshold." Family-wise error rate control is provided through use of closed testing with Simes test. There are some practical functions to play around with the pathways of interest.


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Reference manual

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install.packages("rSEA")

2.1.0 by Mitra Ebrahimpoor, 2 months ago


Browse source code at https://github.com/cran/rSEA


Authors: Mitra Ebrahimpoor


Documentation:   PDF Manual  


GPL (>= 2) license


Depends on hommel

Suggests knitr, rmarkdown


See at CRAN