Methods for Closed Testing with Simes Inequality, in Particular Hommel's Method

Provides methods for closed testing using Simes local tests. In particular, calculates adjusted p-values for Hommel's multiple testing method, and provides lower confidence bounds for true discovery proportions. A robust but more conservative variant of the closed testing procedure that does not require the assumption of Simes inequality is also implemented. The methods have been described in detail in Goeman et al (2016) .


Reference manual

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1.5 by Jelle Goeman, a year ago

Browse source code at

Authors: Jelle Goeman , Rosa Meijer , Thijmen Krebs

Documentation:   PDF Manual  

GPL (>= 2) license

Imports Rcpp, methods

Linking to Rcpp

Imported by ARIbrain, cherry.

Depended on by rSEA.

See at CRAN