Parametric Linkage Analysis

Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via 'MERLIN' (Abecasis et al. (2002) ), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. 'paramlink2' is part of the 'ped suite' package ecosystem, presented in 'Pedigree Analysis in R' (Vigeland, 2021, ISBN:9780128244302).


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install.packages("paramlink2")

1.0.3 by Magnus Dehli Vigeland, 7 months ago


https://github.com/magnusdv/paramlink2


Report a bug at https://github.com/magnusdv/paramlink2/issues


Browse source code at https://github.com/cran/paramlink2


Authors: Magnus Dehli Vigeland [aut, cre]


Documentation:   PDF Manual  


GPL-3 license


Imports pedprobr

Depends on pedtools

Suggests spelling, testthat

System requirements: MERLIN (http://csg.sph.umich.edu/abecasis/merlin/index.html) for multipoint linkage analysis.


Imported by pedsuite.


See at CRAN