Loading NONMEM Output Files and Simulate with Parameter Uncertainty

Loading NONMEM (NONlinear Mixed-Effect Modeling, < http://www.iconplc.com/innovation/solutions/nonmem/> ) output files and simulate with parameter uncertainty.


nonmem2R v0.1.10 (Release date: 2018-09-26)


  • Added vpcfig3 for creating multiple VPC plots from one single PSN vpc output file

  • Added modload for loading model file and print on screen

  • Added stat_QQnorm for Quantile-Quantile plots with ggplot2

  • Added stat_QQCL for confidence intervals for Quantile-Quantile plots with ggplot2

  • Updated vpgfig2; now using geom_ribbon (instead of geom_polygon) for drawing model confidence intervals. This means x-axis limits can be set by e.g. xlim or scale_x_continuous. (Previous version using geom_polygon required using coord_cartesian for setting axis limits to avoid a corrupted VPC.)

nonmem2R v0.1.9 (Release date: 2018-04-06)


  • Added model.path argument to vpcfig & vpcfig2, with similar use of model.path as in e.g. sumoR & extload

  • Add footnote extToTable to keep track if OMEGA and SIGMA are reported as variances or as standard-deviations

  • Updated covload to handle cov files with multiple tables from NONMEM model files with multiple $COV and/or multiple $EST.

  • Fixed column names for covload output

  • Updated help-page for vpcfig2 with advice for setting axis limits

Reference manual

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0.1.10 by Magnus Astrand, 4 months ago

Browse source code at https://github.com/cran/nonmem2R

Authors: Magnus Astrand

Documentation:   PDF Manual  

Unlimited license

Imports mvtnorm, lattice, latticeExtra, MASS, splines2

Depends on ggplot2

See at CRAN