The Group Sequential Max-Combo Test for Comparing Survival Curves

Functions for comparing survival curves using the max-combo test at a single timepoint or repeatedly at successive respective timepoints while controlling type I error (i.e., the group sequential setting), as published by Prior (2020) . The max-combo test is a generalization of the weighted log-rank test, which itself is a generalization of the log-rank test, which is a commonly used statistical test for comparing survival curves, e.g., during or after a clinical trial as part of an effort to determine if a new drug or therapy is more effective at delaying undesirable outcomes than an established drug or therapy or a placebo.


Reference manual

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1.0 by Tom Prior, a year ago

Browse source code at

Authors: Tom Prior

Documentation:   PDF Manual  

GPL-2 license

Imports magrittr, purrr, rlang, mstate, MCMCpack, dplyr, mvtnorm, survival

See at CRAN