Inferring the Topology of Omics Data

Infers a topology of relationships between different datasets, such as multi-omics and phenotypic data recorded on the same samples. We based this methodology on the RV coefficient (Robert & Escoufier, 1976, ), a measure of matrix correlation, which we have extended for partial matrix correlations and binary data (Aben et al., 2018, ).


News

iTOP 1.0.2

Some slight changes to the vignette and adding support for using n x 1 matrices.

iTOP 1.0.1

The iTOP manuscript is now on bioRxiv! Adding the DOI in all relevant places.

iTOP 1.0.0

First release version!

Reference manual

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install.packages("iTOP")

1.0.2 by Nanne Aben, 10 months ago


Browse source code at https://github.com/cran/iTOP


Authors: Nanne Aben


Documentation:   PDF Manual  


GPL-2 license


Imports Matrix, corpcor

Suggests knitr, rmarkdown, NMF, pcalg, Rgraphviz


See at CRAN