Two-Stage Adaptive Dose-Finding Clinical Trial Design

Simulate and implement early phase two-stage adaptive dose-finding design for binary and quasi-continuous toxicity endpoints. See Chiuzan et al. (2018) for further reading .


Reference manual

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2.0.1 by Alyssa Vanderbeek, 6 months ago

Browse source code at

Authors: Alyssa Vanderbeek [aut, cre] , Laura Cosgrove [ctb] , Elizabeth Garrett-Mayer [ctb] , Cody Chiuzan [ctb]

Documentation:   PDF Manual  

LGPL-3 license

Imports Matrix, grDevices, utils

Depends on shiny, shinydashboard

Suggests knitr, rmarkdown

See at CRAN