Calculate the 'Grantham' Distance

A minimal set of routines to calculate the 'Grantham' distance . The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.


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Reference manual

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install.packages("grantham")

0.1.1 by Ramiro Magno, 12 days ago


https://maialab.org/grantham/, https://github.com/maialab/grantham


Report a bug at https://github.com/maialab/grantham/issues


Browse source code at https://github.com/cran/grantham


Authors: Ramiro Magno [aut, cre] , Isabel Duarte [aut] , Ana-Teresa Maia [aut] , CINTESIS [cph, fnd]


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports tibble, magrittr, vctrs, dplyr, tidyr, rlang, stringr

Suggests spelling


Imported by agvgd.


See at CRAN