Endogenous Perturbation Analysis of Cancer

Estimates sparse matrices A or G using fast lasso regression from mRNA transcript levels Y and CNA profiles U. Two models are provided, EPoC A where AY + U + R = 0 and EPoC G where Y = GU + E, the matrices R and E are so far treated as noise. For details see the manual page of 'lassoshooting' and the article Rebecka Jörnsten, Tobias Abenius, Teresia Kling, Linnéa Schmidt, Erik Johansson, Torbjörn E M Nordling, Bodil Nordlander, Chris Sander, Peter Gennemark, Keiko Funa, Björn Nilsson, Linda Lindahl, Sven Nelander (2011) .


Reference manual

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0.2.6-1 by Tobias Abenius, 7 months ago

Browse source code at https://github.com/cran/epoc

Authors: Rebecka Jornsten , Tobias Abenius , Sven Nelander

Documentation:   PDF Manual  

LGPL-3 license

Imports irr, elasticnet, survival

Depends on lassoshooting, Matrix, methods

Suggests graph

See at CRAN