Infer Cell-Cell Communication from Spatial Transcriptomics

Identifies cell-cell communication hotspots in spatial transcriptomics data using bivariate Local Moran's I statistics on hexagonally binned cells. Provides functions for spatial weighting, ligand-receptor pair filtering, hotspot detection, and visualisation of sender-receiver cell-type interactions.

blisa: Cell-cell communication using Bivariate Local Indicator of Spatial Autocorrelation

blisa implements functionalities to study cell-cell communication in spatial transcriptomics experiments using bivariate local indicator of spatial autocorrelation.

Install development version from GitHub

library(devtools)   
devtools::install_github("ChenLaboratory/blisa")