A Spatial Model of Intra-Tumor Heterogeneity

Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) . Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.


Reference manual

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1.1.0 by Phillip B. Nicol, 2 months ago


Report a bug at https://github.com/phillipnicol/SITH/issues

Browse source code at https://github.com/cran/SITH

Authors: Phillip B. Nicol

Documentation:   PDF Manual  

GPL (>= 2) license

Imports Rcpp, scatterplot3d, stats, graphics, grDevices

Suggests rgl, igraph, knitr, rmarkdown, testthat

Linking to Rcpp

See at CRAN