A Spatial Model of Intra-Tumor Heterogeneity

Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) . Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.


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install.packages("SITH")

1.0.1 by Phillip B. Nicol, 4 months ago


https://github.com/phillipnicol/SITH


Report a bug at https://github.com/phillipnicol/SITH/issues


Browse source code at https://github.com/cran/SITH


Authors: Phillip B. Nicol


Documentation:   PDF Manual  


GPL (>= 2) license


Imports Rcpp, scatterplot3d, stats, graphics, grDevices

Suggests rgl, knitr, rmarkdown, testthat

Linking to Rcpp


See at CRAN