Objective Comparison of Phase I Dose-Finding Designs

Generate decision tables and simulate operating characteristics for phase I dose-finding designs to enable objective comparison across methods. Supported designs include the traditional 3+3, Bayesian Optimal Interval (BOIN) (Liu and Yuan (2015) ), modified Toxicity Probability Interval-2 (mTPI-2) (Guo et al. (2017) ), interval 3+3 (i3+3) (Liu et al. (2020) ), and Generalized 3+3 (G3). Provides visualization tools for comparing decision rules and operating characteristics across multiple designs simultaneously.