Differentially Expressed Single Nucleotide Polymorphism

Provides a framework for the identification and analysis of Differentially Expressed Single Nucleotide Polymorphisms (deSNPs) using high-throughput sequencing data. It enables users to import SNP count data from variant files, perform allele-specific read count extraction, and statistically detect SNPs showing significant differences in allele expression between biological conditions or sample groups. This package contains tools for calculating SNP-index and Delta SNP-index from VCF-derived allele depth data with statistical testing and filtering, including sliding-window analysis of genomic regions.


Reference manual

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install.packages("DESNP")

0.1.0 by Sayanti Guha Majumdar, 7 months ago


Browse source code at https://github.com/cran/DESNP


Authors: Sayanti Guha Majumdar [aut, cre] , Saima Bano [aut] , Nandita Banerjee [aut] , Rahul Kumar Tiwari [aut] , Dipro Sinha [aut] , Subham Ghosh [aut] , Sanjeev Kumar [aut]


Documentation:   PDF Manual  


GPL-3 license


Imports vcfR, dplyr, tidyr, magrittr, tidyselect, VGAM, stats, utils, GenomicRanges, IRanges, S4Vectors, GenomeInfoDb, tools, ggplot2


See at CRAN