Automated Transcriptome Classifier Pipeline: Comprehensive Transcriptome Analysis

An unsupervised fully-automated pipeline for transcriptome analysis or a supervised option to identify characteristic genes from predefined subclasses. We rely on the 'pamr' < http://www.bioconductor.org/packages//2.7/bioc/html/pamr.html> clustering algorithm to cluster the Data and then draw a heatmap of the clusters with the most significant genes and the least significant genes according to the 'pamr' algorithm. This way we get easy to grasp heatmaps that show us for each cluster which are the clusters most defining genes.

Configural Frequencies Analysis Using Log-Linear Modeling

Offers several functions for Configural Frequencies Analysis (CFA), which is a useful statistical tool for the analysis of multiway contingency tables. CFA was introduced by G. A. Lienert as 'Konfigurations Frequenz Analyse - KFA'. Lienert, G. A. (1971). Die Konfigurationsfrequenzanalyse: I. Ein neuer Weg zu Typen und Syndromen. Zeitschrift für Klinische Psychologie und Psychotherapie, 19(2), 99–115.

Estimate Global Clustering in Infectious Disease

Implements various novel and standard clustering statistics and other analyses useful for understanding the spread of infectious disease.

Ensemble Clustering using K Means and Hierarchical Clustering

Implements an ensemble algorithm for clustering combining a k-means and a hierarchical clustering approach.

Parallel Processing Options for Package 'dataRetrieval'

Provides methods for retrieving United States Geological Survey (USGS) water data using sequential and parallel processing (Bengtsson, 2022 ). In addition to parallel methods, data wrangling and additional statistical attributes are provided.

Robust Bayesian T-Test

An implementation of Bayesian model-averaged t-tests that allows users to draw inferences about the presence versus absence of an effect, variance heterogeneity, and potential outliers. The 'RoBTT' package estimates ensembles of models created by combining competing hypotheses and applies Bayesian model averaging using posterior model probabilities. Users can obtain model-averaged posterior distributions and inclusion Bayes factors, accounting for uncertainty in the data-generating process (Maier et al., 2024, ). The package also provides a truncated likelihood version of the model-averaged t-test, enabling users to exclude potential outliers without introducing bias (Godmann et al., 2024, ). Users can specify a wide range of informative priors for all parameters of interest. The package offers convenient functions for summary, visualization, and fit diagnostics.

Automated and Early Detection of Disease Outbreaks

A powerful tool for automating the early detection of disease outbreaks in time series data. 'aeddo' employs advanced statistical methods, including hierarchical models, in an innovative manner to effectively characterize outbreak signals. It is particularly useful for epidemiologists, public health professionals, and researchers seeking to identify and respond to disease outbreaks in a timely fashion. For a detailed reference on hierarchical models, consult Henrik Madsen and Poul Thyregod's book (2011), ISBN: 9781420091557.

Fitting (Exponential/Diffusion) RT-MPT Models

Fit (exponential or diffusion) response-time extended multinomial processing tree (RT-MPT) models by Klauer and Kellen (2018) and Klauer, Hartmann, and Meyer-Grant (submitted). The RT-MPT class not only incorporate frequencies like traditional multinomial processing tree (MPT) models, but also latencies. This enables it to estimate process completion times and encoding plus motor execution times next to the process probabilities of traditional MPTs. 'rtmpt' is a hierarchical Bayesian framework and posterior samples are sampled using a Metropolis-within-Gibbs sampler (for exponential RT-MPTs) or Hamiltonian-within-Gibbs sampler (for diffusion RT-MPTs).

Dynamic Models for Confidence and Response Time Distributions

Provides density functions for the joint distribution of choice, response time and confidence for discrete confidence judgments as well as functions for parameter fitting, prediction and simulation for various dynamical models of decision confidence. All models are explained in detail by Hellmann et al. (2023; Preprint available at < https://osf.io/9jfqr/>, published version: ). Implemented models are the dynaViTE model, dynWEV model, the 2DSD model (Pleskac & Busemeyer, 2010, ), and various race models. C++ code for dynWEV and 2DSD is based on the 'rtdists' package by Henrik Singmann.

Complete Functional Regulation Analysis

Calculates complete functional regulation analysis and visualize the results in a single heatmap. The provided example data is for biological data but the methodology can be used for large data sets to compare quantitative entities that can be grouped. For example, a store might divide entities into cloth, food, car products etc and want to see how sales changes in the groups after some event. The theoretical background for the calculations are provided in New insights into functional regulation in MS-based drug profiling, Ana Sofia Carvalho, Henrik Molina & Rune Matthiesen, Scientific Reports .