Infer Gene Probabilistic Boolean Networks from Single-Cell Data

Given a gene regulatory boolean network and a RNA-seq dataset, this package computes protein activity normalised enrichment scores using 'VIPER', and then produces a probabilistic network using the scores as probabilities for fixed node activation or deactivation, in addition to the original Boolean functions. For more information, refer to the preprint: Victori and Buffa (2022) .

A General-Purpose Package for Dynamic Report Generation in R

Provides a general-purpose tool for dynamic report generation in R using Literate Programming techniques.

Bayes Linear Estimators for Finite Population

Allows the user to apply the Bayes Linear approach to finite population with the Simple Random Sampling - BLE_SRS() - and the Stratified Simple Random Sampling design - BLE_SSRS() - (both without replacement), to the Ratio estimator (using auxiliary information) - BLE_Ratio() - and to categorical data - BLE_Categorical(). The Bayes linear estimation approach is applied to a general linear regression model for finite population prediction in BLE_Reg() and it is also possible to achieve the design based estimators using vague prior distributions. Based on Gonçalves, K.C.M, Moura, F.A.S and Migon, H.S.(2014) < https://www150.statcan.gc.ca/n1/en/catalogue/12-001-X201400111886>.

Selecting Variable Subsets

A collection of functions which (i) assess the quality of variable subsets as surrogates for a full data set, in either an exploratory data analysis or in the context of a multivariate linear model, and (ii) search for subsets which are optimal under various criteria. Theoretical support for the heuristic search methods and exploratory data analysis criteria is in Cadima, Cerdeira, Minhoto (2003, ). Theoretical support for the leap and bounds algorithm and the criteria for the general multivariate linear model is in Duarte Silva (2001, ). There is a package vignette "subselect", which includes additional references.

Aggregate Multiple ROC Curves into One Global ROC

Aggregates multiple Receiver Operating Characteristic (ROC) curves obtained from different sources into one global ROC. Additionally, it’s also possible to calculate the aggregated precision-recall (PR) curve.

Efficient Outlier Detection for Large Time Series Databases

Programs for detecting and cleaning outliers in single time series and in time series from homogeneous and heterogeneous databases using an Orthogonal Greedy Algorithm (OGA) for saturated linear regression models. The programs implement the procedures presented in the paper entitled "Efficient Outlier Detection for Large Time Series Databases" by Pedro Galeano, Daniel Peña and Ruey S. Tsay (2026), working paper, Universidad Carlos III de Madrid. Version 1.1.2 fixes one bug.

Helper Functions for Species Delimitation Analysis

Helpers functions to process, analyse, and visualize the output of single locus species delimitation methods. For full functionality, please install suggested software at < https://legallab.github.io/delimtools/articles/install.html>.

Robust Selection Algorithm

An implementation of algorithms for estimation of the graphical lasso regularization parameter described in Pedro Cisneros-Velarde, Alexander Petersen and Sang-Yun Oh (2020) < http://proceedings.mlr.press/v108/cisneros20a.html>.

Spatial Regression Analysis

A collection of all the estimation functions for spatial cross-sectional models (on lattice/areal data using spatial weights matrices) contained up to now in 'spdep'. These model fitting functions include maximum likelihood methods for cross-sectional models proposed by 'Cliff' and 'Ord' (1973, ISBN:0850860369) and (1981, ISBN:0850860814), fitting methods initially described by 'Ord' (1975) . The models are further described by 'Anselin' (1988) . Spatial two stage least squares and spatial general method of moment models initially proposed by 'Kelejian' and 'Prucha' (1998) and (1999) are provided. Impact methods and MCMC fitting methods proposed by 'LeSage' and 'Pace' (2009) are implemented for the family of cross-sectional spatial regression models. Methods for fitting the log determinant term in maximum likelihood and MCMC fitting are compared by 'Bivand et al.' (2013) , and model fitting methods by 'Bivand' and 'Piras' (2015) ; both of these articles include extensive lists of references. A recent review is provided by 'Bivand', 'Millo' and 'Piras' (2021) . 'spatialreg' >= 1.1-* corresponded to 'spdep' >= 1.1-1, in which the model fitting functions were deprecated and passed through to 'spatialreg', but masked those in 'spatialreg'. From versions 1.2-*, the functions have been made defunct in 'spdep'. From version 1.3-6, add Anselin-Kelejian (1997) test to `stsls` for residual spatial autocorrelation .

An Interface to IMF (International Monetary Fund) Data JSON API

A straightforward interface for accessing the IMF (International Monetary Fund) data JSON API, available at < https://data.imf.org/>. This package offers direct access to the primary API endpoints: Dataflow, DataStructure, and CompactData. And, it provides an intuitive interface for exploring available dimensions and attributes, as well as querying individual time-series datasets. Additionally, the package implements a rate limit on API calls to reduce the chances of exceeding service limits (limited to 10 calls every 5 seconds) and encountering response errors.