Tidy Model Visualisation for Generalised Additive Models

Provides functions for visualising generalised additive models and getting predicted values using tidy tools from the 'tidyverse' packages.

Self-Controlled Cohort Population-Level Estimation

Estimates incidence rate ratios by comparing time exposed with time unexposed among an exposed cohort using self-controlled cohort methodology as described in Ryan et al. (2013) . Functions used for empirical calibration of effect estimates, confidence intervals, and p-values are included to control for residual bias.

Cohort Generation for the OMOP Common Data Model

Generate cohorts and subsets using an Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) Database. Cohorts are defined using 'CIRCE' (< https://github.com/ohdsi/circe-be>) or SQL compatible with 'SqlRender' (< https://github.com/OHDSI/SqlRender>).

Develop Clinical Prediction Models Using the Common Data Model

A user friendly way to create patient level prediction models using the Observational Medical Outcomes Partnership Common Data Model. Given a cohort of interest and an outcome of interest, the package can use data in the Common Data Model to build a large set of features. These features can then be used to fit a predictive model with a number of machine learning algorithms. This is further described in Reps (2017) .

Generating Features for a Cohort

An R interface for generating features for a cohort using data in the Common Data Model. Features can be constructed using default or custom made feature definitions. Furthermore it's possible to aggregate features and get the summary statistics.

Achilles Data Source Characterization

Automated Characterization of Health Information at Large-Scale Longitudinal Evidence Systems. Creates a descriptive statistics summary for an Observational Medical Outcomes Partnership Common Data Model standardized data source. This package includes functions for executing summary queries on the specified data source and exporting reporting content for use across a variety of Observational Health Data Sciences and Informatics community applications.

Cyclic Coordinate Descent for Logistic, Poisson and Survival Analysis

This model fitting tool incorporates cyclic coordinate descent and majorization-minimization approaches to fit a variety of regression models found in large-scale observational healthcare data. Implementations focus on computational optimization and fine-scale parallelization to yield efficient inference in massive datasets. Please see: Suchard, Simpson, Zorych, Ryan and Madigan (2013) .